Antimicrobial compositions comprising minocycline and degradation products of oxidized cellulose
AssigneesOmrix Biopharmaceuticals Ltd., Ethicon, Inc.
InventorsEve Montia, Dwayne Looney, Theresa Scheuble, Ronen Eavri, Roi Mashiach
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Abstract
Provided is an antimicrobial composition comprised of at least one degradation product of oxidized cellulose (OC), such as oxidized regenerate cellulose (ORC), and minocycline, methods of preparation thereof and uses thereof.
Claims5
A method for the treatment of an infection in a subject in need thereof, the method comprising administering to the subject an antimicrobial composition comprising an extract of at least one degradation product of an oxidized regenerated cellulose (ORC) substrate in a solid form, and an antibiotic being minocycline, wherein the at least one degradation product comprises one or more members selected from the group consisting of a monosaccharide and an oligosaccharide, and wherein the carboxyl content of the ORC is about 12% to about 21%, by weight.
Dependencies are inferred from the claim text.