Compositions and methods of interferon alpha binding proteins
AssigneesMeiogen Biotechnology Corporation, The United States Government as represented by the Department of Veterans Affairs
InventorsWilliam Tyor, Rajeth Koneru, Jennifer Ward, Leonard Maroun
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Abstract
Disclosed are compositions comprising an interferon-alpha binding protein and combined anti-retroviral therapy (cART). In some aspects, the interferon-alpha binding protein is B18R. In some aspects, the compositions further comprise a pharmaceutically acceptable carrier. Disclosed are methods of treating a subject with HIV associated neurogenerative disorder (HAND) comprising administering a therapeutically effective amount of B18R and cART. Disclosed are methods of reversing behavioral abnormalities in subjects having HAND comprising administering a therapeutically effective amount of B18R.
Claims5
A method of treating a subject with HW associated neurodegenerative disorder (HAND) comprising administering to the subject with HAND a therapeutically effective amount of B18R (SEQ ID NO:1) and combined anti-retroviral therapy (cART).
Dependencies are inferred from the claim text.