Lactobacillus plant arum strain, polysaccharides derived from strain, and use thereof

A method of immune modulation comprising administering a polysaccharide represented by Formula I below to a subject:

• -[-D-B-I-F-G-C-E-H-A-]n- [Formula I]
• in Formula I,
• A and D are galactose,
• B, C, E, G, and H are rhamnose,
• F is N-acetylglucosamine,
• I is glucose, and
• n is an integer of 1 or more.

A method of producing inflammatory T cells, comprising:

• (a) priming antigen-presenting cells with a Lactobacillus plantarum IMB19 strain having accession number KCTC 14337BP or a polysaccharide represented by Formula I below:
• -[-D-B-I-F-G-C-E-H-A-]n- [Formula I]
• in Formula I,
• A and D are galactose,
• B, C, E, G, and H are rhamnose,
• F is N-acetylglucosamine,
• I is glucose, and
• n is an integer of 1 or more;
• and
• (b) co-culturing the primed antigen-presenting cells with T cells.

A method of producing M1-phenotype macrophages, comprising:

• differentiating macrophages into M1-phenotype macrophages by treating macrophages with a Lactobacillus plantarum IMB19 strain having accession number KCTC 14337BP or a polysaccharide represented by Formula I below:
• -[-D-B-I-F-G-C-E-H-A-]n- [Formula I]
• in Formula I,
• A and D are galactose,
• B, C, E, G, and H are rhamnose,
• F is N-acetylglucosamine,
• I is glucose, and
• n is an integer of 1 or more;
• and
• obtaining the differentiated M1-phenotype macrophages.