Use of Coriobacteriia to promote gut health
AssigneeErber Aktiengesellschaft
InventorsDian Schatzmayr, Eva Maria Binder, Veronika Nagl, Gerd Schatzmayr
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Abstract
The present invention relates to a use of a microorganism of the class Coriobacteriia for promoting gut health of a healthy subject. Also provided is a method for the production of chenodeoxycholic acid (CDCA) and a method for the production of lithocholic acid (LCA).
Claims14
A method of increasing the bile acid(s) glycolithocholic acid (GLCA) and/or taurolitocholic acid (TLCA) within a subject compared to GCLA and/or TLCA present before administration of the microorganism comprising administering to a healthy subject a microorganism of the class Coriobacteriia and the order Eggerthellales, wherein the microorganism is provided within a food and/or feed composition, wherein administering causes an increase in GLCA and/or TLCA within the subject, and wherein the food- and/or feed composition without the microorganism therein, when administered to the subject, does not have a toxic effect on the subject.
A method of promoting intestinal integrity of a healthy subject, comprising administering to the healthy subject a microorganism of the class Coriobacteriia and the order Eggerthellales, wherein administering causes intestinal integrity which is, in the least, characterized by a test which feeds lactulose and rhamnose to the subject, measures a lactulose/rhamnose ratio in urine 6 hours after feeding, and determines said lactulose/rhamnose ratio is lower than a lactulose/rhamnose ratio in urine at the time point of feeding, and wherein the food- and/or feed composition without the microorganism therein, when administered to the subject, does not have a toxic effect on the subject.
Dependencies are inferred from the claim text.