Pharmaceutical composition for oral administration containing sulfasalazine and/or a sulfasalazine organic salt, production process and use
AssigneeMedac Gesellschaft Fuer Klinische Spezialpraeparate Mbh
InventorsMarguerite Mensonides-Harsema, Sebastian Bialleck, Sonja Schuldt-Lieb
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Abstract
Disclosed is to a new pharmaceutical composition for oral administration containing sulfasalazine and/or a sulfasalazine organic salt, production processes and uses, in particular in the treatment of a disease or condition in which modulation of inflammatory cells is beneficial, a disease or condition concerning bones or joints and/or the gastro-intestinal tract.
Claims25
A process for preparing a pharmaceutical composition for oral administration comprising 2-hydroxy-5-[2-[4-[(2-pyridinylamino)sulfonyl]phenyl]diazenyl]-benzoic acid (sulfasalazine) and/or a sulfasalazine organic salt, the process comprising the following steps:
- A:
- Providing sulfasalazine,
- B:
- Providing an organic amine containing constituent,
- C:
- Providing one or more pharmaceutical excipients and optionally one or more further active ingredients,
- D:
- Mixing a therapeutically effective amount of sulfasalazine of step A) with a suitable amount of the organic amine containing constituent of step B) and the one or more pharmaceutical excipients and optionally one or more further active ingredient of step C) to form the pharmaceutical composition for oral administration,
- wherein the organic amine containing constituent does not represent Tris(hydroxymethyl)aminomethane.
Dependencies are inferred from the claim text.