Non-hormonal steroid modulators of NF-κβ for treatment of disease
AssigneeReveraGen BioPharma, Inc.
InventorsJohn M. McCall, Eric Hoffman, Kanneboyina Nagaraju, Jesse Damsker
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Abstract
The present invention relates to compounds and methods which may be useful as treatments of diseases.
Claims13
A method of treating or reducing the symptoms of muscular dystrophy by increasing percentage of ejection fraction and increasing percentage of fraction shortening in a patient, the method comprising the administration, to the patient in need thereof, of a therapeutically effective amount of a compound for treating the muscular dystrophy, the compound having the structural formula
- or a salt thereof,
- wherein the therapeutically effective amount is greater than or equal to 2 mg/kg/day.
A method of treating or reducing the symptoms of muscular dystrophy comprising the oral administration, to a patient in need thereof, of a therapeutically effective amount of
- or a salt thereof,
- wherein the therapeutically effective amount is greater than or equal to 2 mg/kg/day;
- and
- the patient, following the administration, having improved ejection fraction and fraction shortening as measured by echocardiography.
Dependencies are inferred from the claim text.