Methods for treating ocular Demodex using lotilaner formulations
AssigneeTarsus Pharmaceuticals, Inc.
InventorsBobak Robert Azamian, Douglas Michael Ackermann, Shawn D. Hickok, Joseph G. Vehige
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Abstract
Disclosed herein are methods for treating or preventing ophthalmic and dermatologic conditions in a patient, including ocular surface conditions such as blepharitis. The methods can include topically administering directly to an ocular surface of one or more eyes of a patient in need of treatment thereof an effective amount of an isoxazoline parasiticide, formamidine parasiticide, or other active ingredient, formulated into an ophthalmic composition, the ophthalmic composition further comprising a pharmaceutically acceptable vehicle. Compositions are also disclosed.
Claims20
A method for treating blepharitis caused by Demodex mites, comprising:
- topically administering directly to an ocular surface of one or more eyes of a human patient in need of treatment thereof an effective amount of an ophthalmic composition,
- wherein the ophthalmic composition comprises lotilaner and a pharmaceutically acceptable vehicle, and
- wherein the ophthalmic composition is in eye drop form.
A method for treating eyelid margin redness caused by Demodex mites, comprising:
- topically administering directly to one or more of the eye, eyelids, or eyelashes of a human patient in need of treatment thereof an effective amount of an ophthalmic composition,
- wherein the ophthalmic composition comprises lotilaner and a pharmaceutically acceptable vehicle, and
- wherein the ophthalmic composition is in eye drop form.
A method for eradicating Demodex mites, comprising:
- topically administering directly to an ocular surface of one or more eyes of a human patient in need of treatment thereof an effective amount of an ophthalmic composition,
- wherein the ophthalmic composition comprises lotilaner and a pharmaceutically acceptable vehicle, and
- wherein the ophthalmic composition is in eye drop form.
Dependencies are inferred from the claim text.