Ophthalmic emulsion

An ophthalmic emulsion, the emulsion comprising:

• water forming an aqueous phase;
• oil forming an oil phase, wherein the oil is at least 0.1 w/v % and not greater than 5 w/v % of the emulsion;
• a hydrophilic surfactant having an HLB value of at least 8, wherein the hydrophilic surfactant is present in the emulsion in an amount that is at least 0.08 w/v % and no greater than 0.8 w/v %;
• a hydrophobic surfactant having an HLB value of below 8, wherein the hydrophobic surfactant is present in the emulsion in an amount that is at least 0.11 w/v % and no greater than 2.0 w/v %;
• an anionic phospholipid;
• borate;
• a mucoadhesive galactomannan polymer, wherein the mucoadhesive galactomannan polymer is present in the emulsion in a concentration of at least 0.01 w/v %, but no greater than 1.0 w/v %;
• wherein the emulsion is free of a benzalkonium chloride,
• wherein:
• i. the oil phase is in droplets within the aqueous phase and the droplets have an average diameter that is no greater than about 1000 nm, but is at least 10 nm, wherein the average diameter is corresponding to 90% of the cumulative undersize distribution by volume measured using a Microtrac S3500 Particle Size Analyzer (Software Version 10.3.1);
• and
• ii. the borate and galactomannan polymer cooperatively act to form a gel upon instillation of the emulsion in an eye of an individual.