Hyperspectral imaging method and device

A device for providing medical information of a region of interest (ROI) of a subject, the device comprising:

• a processor and memory addressable by the processor, the memory storing one or more programs for execution by the processor, the one or more programs comprising instructions for performing a method comprising:
• obtaining a first spectral image dataset of the ROI, wherein the first spectral image dataset comprises a first plurality of signal arrays, and each respective signal array in the first plurality of signal arrays is characterized by a single corresponding spectral band in a first plurality of spectral bands, wherein each spectral band in the first plurality of spectral bands is within a first spectral range that penetrates tissue with a first average depth;
• obtaining a second spectral image dataset of the ROI, wherein the second spectral image dataset comprises a second plurality of signal arrays, and each respective signal array in the second plurality of signal arrays is characterized by a single corresponding spectral band in a second plurality of spectral bands, wherein each spectral band in the second plurality of spectral bands is within a second spectral range that is different than the first spectral range that penetrates tissue with a second average depth, wherein the second average depth is deeper than the first average depth;
• performing a first spectral analysis on the first spectral image dataset to determine first concentration values of each spectral signature in a first spectral signature set at each respective point in an array of points corresponding to a two-dimensional area of the ROI, wherein the first spectral signature set comprises a first spectral signature;
• performing a second spectral analysis on the second spectral image dataset to determine second concentration values of each spectral signature in a second spectral signature set at each respective point in the array of points, wherein the second spectral signature set comprises the first spectral signature;
• and
• generating third concentration values of each spectral signature in a third spectral signature set at each respective point in the array of points, wherein the third spectral signature set comprises the first spectral signature, wherein the third concentration values of the first spectral signature are generated by compensating the second concentration values of the first spectral signature with the first concentration values of the first spectral signature at each respective point in the array of points.