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US 11,685,902 B2Granted
Production method for kidney-like tissue
AssigneeTokushima University
InventorHideharu Abe
Life of this patent
Estimating the term…
Abstract
A novel tissue usable for a kidney tissue model is provided. A method for producing a kidney-like tissue includes co-culturing a cell group containing mesenchymal stem cells, vascular endothelial cells, and clonal embryonic kidney cells.
Claims14
A method for producing a kidney-like tissue, the method comprising:
- co-culturing a cell group containing a mesenchymal stem cell, a vascular endothelial cell, and a clonal embryonic kidney cell to generate tissues, and
- selecting from the tissues, as a kidney-like tissue, a microsphere positive for expression of at least one member selected from the group consisting of Wilms tumor-1, nephrin, and podocin.
A method for producing a kidney-like tissue, the method comprising:
- co-culturing a cell group containing a mesenchymal stem cell, a vascular endothelial cell, and a clonal embryonic kidney cell,
- wherein the cell group further contains a renal tubular cell and/or a mesangial cell.
Dependencies are inferred from the claim text.