Anti-human LAG-3 monoclonal antibody and use thereof

An antibody, that binds to LAG-3 comprising:

• (1) a heavy chain variable region comprising the following three complementary determining regions (CDRs):
• CDR1 having the amino acid sequence of SEQ ID NO:
• 2;
• CDR2 having the amino acid sequence of SEQ ID NO:
• 3;
• and
• CDR3 having the amino acid sequence of SEQ ID NO:
• 4;
• and
• (2) a light chain variable region comprising the following three complementary determining regions (CDRs):
• CDR1′ having the amino acid sequence of SEQ ID NO:
• 6;
• CDR2′ having the amino acid sequence of SEQ ID NO:
• 7 or SEQ ID NO:
• 84;
• and
• CDR3′ having the amino acid sequence of SEQ ID NO:
• 8.