Closed-loop multi-channel asynchronous neurostimulator to mimic neural code for cognitive prosthesis
AssigneeUniversity of Southern California
InventorsDong Song, Theodore W. Berger, Sahar Elyahoodayan
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Abstract
A method for providing stimulation of living tissue may include generating electrical pulses onto multiple output channels to a plurality of electrodes each corresponding to one of the multiple output channels. The method may also include disconnecting the plurality of electrodes from recording amplifiers during a stimulation. Additionally, the method may include shorting, after each stimulation before recording is resumed, inputs of the recording amplifiers to ground to suppress ringing in the recording system.
Claims16
A system for providing stimulation of living tissue, the system comprising:
- a de-multiplexer control unit for receiving a plurality of sequences of temporal electrical pulses and for generating a plurality of control signals based on the plurality of sequences of temporal electrical pulses;
- a stimulation generator configured to generate a signal on a single channel, the signal comprising a sequence of temporal electrical pulses based on the plurality of sequences of temporal electrical pulses, each one of the plurality of sequences of temporal electrical pulses corresponding to a spatial location and a channel of a plurality of spatial channels;
- a de-multiplexer for receiving the sequence of temporal electrical pulses and the plurality of control signals and for generating a reconstructed plurality of sequences of temporal electrical pulses on a plurality of output channels based on the sequence of temporal electrical pulses and based on the plurality of control signals from the de-multiplexer control unit;
- and
- a plurality of electrodes each corresponding to one of the plurality of output channels, wherein each of the plurality of output channels, and each associated electrode of the plurality of electrodes, is associated with a different spatial location on the living tissue.
A method for providing spatiotemporal stimulation of living tissue, the method comprising:
- generating, at a de-multiplexer control unit, a plurality of control signals based ona plurality of sequences of temporal electrical pulses;
- generating, at a stimulation generator, a sequence of temporal electrical pulses based on input from the plurality of sequences of temporal electrical pulses, each one of the plurality of sequences of temporal electrical pulses corresponding to a spatial location and a channel of a plurality of spatial channels;
- generating, at a de-multiplexer, a reconstructed plurality of sequences of temporal electrical pulses onto a plurality of output channels based on the sequence of temporal electrical pulses and based on the plurality of control signals from the de-multiplexer control unit, wherein each of the plurality of output channels is associated with a corresponding one of a plurality of electrodes;
- disconnecting the plurality of electrodes from recording amplifiers during a stimulation;
- and
- shorting, after each stimulation before recording is resumed, inputs of the recording amplifiers to ground to suppress ringing in a recording module.
A system for providing stimulation of living tissue, the system comprising:
- means for generating a plurality of control signals based on a plurality of sequences of temporal electrical pulses;
- means for generating a sequence of temporal electrical pulses based on input from the plurality of sequences of temporal electrical pulses, each one of the plurality of sequences of temporal electrical pulses corresponding to a spatial location and a channel of a plurality of spatial channels, and for generating a reconstructed plurality of sequences of temporal electrical pulses onto a plurality of output channels based on the sequence of temporal electrical pulses, wherein each of the plurality of output channels is associated with a corresponding one of a plurality of electrodes;
- means for disconnecting the plurality of electrodes from recording amplifiers during a stimulation;
- and
- means for shorting, after each stimulation before recording is resumed, inputs of the recording amplifiers to ground to suppress ringing in a recording module.
Dependencies are inferred from the claim text.