Closed-loop actuating and sensing epidermal systems
AssigneeThe Regents of the University of California
InventorSheng Xu
Life of this patent
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Abstract
A closed-loop wearable device or platform integrates sensors, actuators, and microcontroller on board. The device is applied directly to the skin using stretchable epidermal electronics. It can sense a variety of signals from the human body, thus collecting medically relevant information, and can activate delivery of a therapeutic upon detection of an abnormal condition. The therapeutic can be delivered at a personalized dosage and/or with a unique combination of drugs or other agents based on the individual's metabolism as tracked by various sensor modules integrated with the medical device.
Claims16
A wearable medical device, comprising:
- a first elastically stretchable or flexible substrate that is removably attachable to an epidermis of a user by van der Waals forces alone;
- at least one biosensor located on the substrate for measuring at least one physiological parameter or vital sign of the user while the substrate is attached to the user;
- at least one actuator located on the substrate for delivering at least one action to the user while the substrate is attached to the user;
- a stretchable microcontroller circuit mounted on the substrate, the stretchable microcontroller circuit being operatively associated with the at least one biosensor and the at least one actuator such that the at least one actuator, responsive to a control signal received from the stretchable microcontroller circuit, delivers at least one action to the user in a closed-loop manner without any external intervention based at least in part data received by the stretchable microcontroller circuit from the at least one biosensor, the stretchable microcontroller circuit being releasably connectable to the at least one biosensor and the at least one actuator, wherein the stretchable microcontroller circuit is encapsulated in a containment chamber having a liquid material therein for reducing strain, the stretchable microcontroller circuit being configured to distinguish between normal and abnormal levels of the at least one physiological parameter of the user and to cause the at least one actuator to be active when an abnormal level of the at least one physiological parameter is detected;
- and
- electrical interconnects each having a self-similar serpentine configuration and electrically interconnecting the at least one biosensor, the at least one actuator and the stretchable microcontroller circuit such that the at least one biosensor, the at least one actuator and the stretchable microcontroller circuit define a common stretchable or flexible package that is able to directly adhere to skin via van der Waals forces alone and is able to naturally deform with the skin.
Dependencies are inferred from the claim text.