Device for the selective removal of molecules from tissues or fluids
AssigneeFundacion De Neurociencias
InventorManuel Menendez Gonzalez
Life of this patent
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Abstract
An implantable device is for the selective removal of molecules from tissues or fluids so as to allow the selective removal of a particular molecule of interest (target molecule) from any type of fluid solution or tissue, including biological tissues or fluids. The device operates through the complementary action of specific-binding molecules (antibodies) directed against the target molecule inside the device. The device includes a nanoperforated membrane having pores larger than the target molecule but smaller than the antibodies, such that the fluid can be removed through a second catheter with a lower concentration of target molecules.
Claims4
A device for selective removal of molecules from tissues or fluids, wherein the tissues or fluids comprise target molecules and natural antibodies, wherein said device comprises:
- a main catheter which can be inserted through a body surface, until said main catheter reaches the fluid or the tissue from which selective removal of molecules is desired, the main catheter being configured for inserting specific antibodies or aptamers against the target molecules;
- a main chamber in which the main catheter terminates;
- a first nanomembrane is positioned in the main chamber and having a pore size larger than that of the target molecules, but smaller than that of the antibodies;
- and
- a second catheter in communication with the main chamber through a second nanomembrane, having a pore size larger than that of the target molecules, but smaller than that of the antibodies, said second catheter thereby providing for removing and filtering fluid treated with the specific antibodies or aptamers and consequently having a lower concentration of target molecules.
Dependencies are inferred from the claim text.