Techniques to reduce risk of occlusions in drug delivery systems
AssigneeInsulet Corporation
InventorsYibin Zheng, Joon Bok Lee, Jason O'Connor
Life of this patent
Estimating the term…
Abstract
Disclosed are techniques to establish a modified pump rate that mitigates the effects of a pump occlusion and enables a recommended dosage of insulin to be output by a pump mechanism over the course of a control cycle. In an example, the pump rate may be reduced by adding a calculated time interval between application of actuation commands to extend the amount of time over which insulin may be output by the pump mechanism.
Claims20
A non-transitory computer readable medium embodied with programming code executable by a processor, and the processor when executing the programming code is operable to:
- receive a control instruction to deliver a dosage of a liquid drug, wherein the control instruction includes an amount of the liquid drug to be delivered during a control cycle;
- determine a number of pulses of a pump mechanism needed to output the dosage of the liquid drug included in the control instruction;
- modify a pump rate for delivery of the dosage of the liquid drug by adding additional time to provide an extended time period for outputting the dosage of the liquid drug during the control cycle;
- and
- output an actuation command to actuate a pump mechanism to output the dosage of the liquid drug included in the control instruction at the modified pump rate.
A drug delivery device, comprising:
- a reservoir operable to hold a liquid drug;
- a cannula coupled to the reservoir via a fluid delivery path and operable to output the liquid drug to a user;
- a pump mechanism coupled to the reservoir and operable to output the liquid drug from the reservoir via the fluid delivery path and out of the cannula;
- a memory operable to store programming code, applications including a delivery control application, and data;
- a controller communicatively coupled to the pump mechanism and the memory, and operable to execute programming code and the applications including the delivery control application;
- and
- a communication device operable to wirelessly communicate with an external device and communicatively coupled to the controller, wherein:
- the controller, when executing the delivery control application, is operable to:
- receive, from the external device, a control instruction including a dosage of the liquid drug to be output by the pump mechanism, wherein the received control instruction indicates an amount of the liquid drug to be output for a control cycle;
- calculate an output distribution of the dosage of the liquid drug by the pump mechanism, wherein the output distribution is a series of partial liquid drug doses output at discrete times distributed over the control cycle;
- and
- output an actuation command to actuate the pump mechanism to deliver a partial liquid drug dose in the series of partial liquid drug doses.
A method, comprising:
- receiving a control instruction to deliver a dosage of a liquid drug, wherein the control instruction includes a dosage of the liquid drug to be output as a pump mechanism;
- determining a plurality of doses of the liquid drug, a sum of which equals the dosage of the liquid drug, to be delivered based on a duration of a control cycle;
- and
- outputting a series of actuation commands, wherein:
- the series of actuation commands includes a number of actuation commands equal to a number of doses of the liquid drug in the plurality of doses of the liquid drug, each actuation command in the series of actuation commands actuates a pump mechanism to output a respective dose of the liquid drug of the plurality of doses of the liquid drug, and each actuation command is applied after passage of a selected additional time period based on the duration of the control cycle.
Dependencies are inferred from the claim text.