Thermosensitive chitosan hydrogel composition and bioink composition comprising the same
AssigneeMedifab Co., Ltd.
InventorsMi Sun Cha, Jung Ju Kim
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Abstract
Provided is a chitosan hydrogel composition including chitosan, glycerol, and a phosphate group, wherein the chitosan is crosslinked via the glycerol, the phosphate group, or a combination thereof. The temperature at which the chitosan hydrogel composition may be induced from a liquid state into a gel state may be controlled according to the content ratio of the phosphate group and the glycerol, and since printing properties and strength are affected by the gelatin concentration, the composition may be used as an ink for 3D printing.
Claims10
A chitosan hydrogel composition comprising chitosan, glycerol, and a phosphate group, wherein the chitosan comprises a first chitosan and a second chitosan crosslinked with each other,
- wherein the glycerol and phosphate group are used as crosslinking agents,
- wherein the glycerol and the phosphate group are comprised at a molar ratio of 1:1 to 1:4,
- wherein gelation of the composition occurs at 15° C. to 60° C., and
- wherein the composition forms a laminated structure when used as an ink for 3D printing.
Dependencies are inferred from the claim text.