Pharmaceutical composition for preventing and treating cell proliferative disease comprising mixture of feather of birds and scale of fish as an active ingredient

A method for treating cell proliferative diseases comprising administering to a subject in need thereof a composition comprising 70˜85 weight % of a feather of bird and 15˜30 weight % of a scale of fish as an active ingredient, wherein a scale of fish is prepared by a method comprising the steps of:

• (a) immersing a fish in water of 20° C.˜77° C. for 1 minute to 2 hours, and separating and washing a scale of the fish;
• (b) immersing and sterilizing the scale washed in the step (a) in 0.1˜0.2 weight % (w/v) NaCl solution for 5 minutes to 1 hour;
• (c) immersing and sterilizing the scale immersed in the step (b) in 1˜3 weight % (v/v) vinegar solution for 15˜20 minutes;
• (d) drying the scale immersed in the step (c) at 30° C.˜70° C. for 5 minutes to 48 hours;
• (e) sterilizing the scale dried in the step (d) by irradiating with 10˜400 nm UV for 10 minutes to 2 hours;
• (f) cutting the scale sterilized in the step (e) to 2˜7 mm for easier grinding;
• (g) sterilizing the scale cut in the step (f) by irradiating with 10˜400 nm UV for 10 minutes to 2 hours;
• (h) grinding the scale sterilized in the step (g) using a grinding machine;
• and
• (i) sterilizing the powder resulting from the step (h) by irradiating with 10˜400 nm UV for 10 minutes to 2 hours.

A method for treating cell proliferative diseases comprising administering to a subject in need thereof a composition comprising 70˜85 weight % of a feather of bird and 15˜30 weight % of a scale of fish as an active ingredient, further wherein the composition further comprises a scale transformed from the dermis, a degenerated or cornified variant of a scale, or a scale or horny scale of reptiles as an active ingredient, wherein the scale transformed from the dermis, the degradated or cornified variant of a scale, or the scale or horny scale of reptiles is prepared by a method comprising the steps of:

• (a) applying physical force to a dead body of fish or reptiles so as to separate the scale or skin;
• (b) sterilizing the separated scale or skin in brine with a salinity from 4.0 to 6.0 for 10 minutes to 2 hours;
• (c) immersing the scale or skin in 1˜3% (v/v) vinegar solution for 10˜20 minutes and sterilizing;
• (d) washing the scale or skin with flowing water to remove impurities;
• (e) drying the washed scale or skin at 20° C.˜70° C. for 5 minutes to 72 hours;
• (f) sterilizing the dried scale or skin by irradiating with 10˜400 nm UV for 10 minutes to 2 hours;
• (g) cutting the scale or skin to 3˜4 mm in width and length;
• (h) sterilizing the cut scale or skin by irradiating with 10˜400 nm UV for 10 minutes to 2 hours;
• (i) grinding the scale or skin using a grinding machine;
• and
• (j) sterilizing the resulting powder by irradiating with 10˜400 nm UV for 10 minutes to 2 hours.