US 11,684,622 B2Granted

Deuterated RUC-4

AssigneeCeleCor Therapeutics, Inc.

InventorYatindra Joshi

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Provided herein are deuterated RUC-4 compounds, and related compositions and therapeutic methods.

Dependent claims

A compound of Formula (I):

or a pharmaceutically acceptable salt thereof, wherein:
each of Ra, Rb, Rc, Rd, R1, R2, R3, R4, R6, R7, R8, R9, R10, R11, R12, R13, R14, and R15 independently are hydrogen or deuterium;
provided that at least one of R1, R2, R3, R4, R6, R7, R8, R9, R10, R11, R12, R13, R14, and R15 is deuterium.

Dependencies are inferred from the claim text.

A61K 31/519
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim: ortho- or peri-condensed with heterocyclic rings
A61K 31/122
Ketones: having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
A61K 31/37
Having six-membered rings, e.g. delta-lactones: coumarins, e.g. psoralen
A61K 31/4365
Ortho- or peri-condensed with heterocyclic ring systems: the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine

From the US filing history. Foreign family members aren’t listed.

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