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US 11,684,618 B2Granted
Compositions comprising mixtures of compounds and uses thereof
AssigneeProstasis Corporation
InventorsMark Brosso, Nicholas Allen Moore
Life of this patent
Estimating the term…
Abstract
Provided herein are compositions comprising niacin, berberine, one or more of silymarin, silibinin, and Siliphos®, lipoic acid, taurine, and phosphatidylcholine. Such compositions are useful for treating or preventing obesity, metabolic and hepatic and neurodegenerative disorders.
Claims18
A composition comprising:
- (a) niacin, or a pharmaceutically acceptable salt thereof;
- (b) berberine, or a pharmaceutically acceptable salt thereof;
- (c) silymarin, silibinin, or Siliphos® (formulated silibinin), or any combination thereof, or a pharmaceutically acceptable salt thereof;
- (d) lipoic acid, or a pharmaceutically acceptable salt thereof;
- (e) taurine, or a pharmaceutically acceptable salt thereof;
- and
- (f) phospholipid or a pharmaceutically acceptable salt thereof;
- wherein the silymarin, silibinin, Siliphos® (formulated silibinin), any combination thereof, or pharmaceutically acceptable salt thereof, is complexed with the phospholipid;
- wherein the niacin, or the pharmaceutically acceptable salt thereof, is in an amount from about 20% to about 40% by weight;
- wherein the berberine, or the pharmaceutically acceptable salt thereof, is in an amount from about 10% to about 20% by weight;
- wherein the silymarin, or the pharmaceutically acceptable salt thereof, the silibinin, or the pharmaceutically acceptable salt thereof, and/or the Siliphos® (formulated silibinin), or the pharmaceutically acceptable salt thereof, combined, are in an amount from about 8% to about 20% by weight;
- wherein the lipoic acid, or the pharmaceutically acceptable salt thereof, is in an amount from about 5% to about 15% by weight;
- wherein the taurine, or the pharmaceutically acceptable salt thereof, is in an amount from about 20% to about 35% by weight;
- and
- wherein the phospholipid, or the pharmaceutically acceptable salt thereof, is in an amount selected from about 5% to about 20% by weight.
12 more elements
Dependencies are inferred from the claim text.