Characterization of the oral microbiome for the non-invasive diagnosis of Barrett's esophagus
AssigneeThe Trustees of Columbia University in the City of New York
InventorJulian Abrams
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Abstract
The present invention relates to noninvasive microbiome analyses of Barrett's esophagus (BE) patients in which changes in the relative abundance of certain bacteria indicate a disease likelihood or pathogenic state. Additional aspects of the present invention relate to manipulating the microbiome to treat or prevent BE and related conditions. Embodiments also include monitoring for development of disease or monitoring treatment for prevention or elimination of disease states.
Claims8
A method for treating or preventing Barrett's esophagus (BE) and related conditions in a mammal, the method comprising orally applying an antimicrobial or antiseptic rinse at least once daily to the mammal,
- wherein the antimicrobial or antiseptic rinse comprises chlorhexidine.
Dependencies are inferred from the claim text.