US 11,684,594 B2Granted

Antifungal prophylaxis for cornea

AssigneePresident and Fellows of Harvard College

InventorsSamir Mitragotri, Eden E. L. Tanner

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The technology described herein is directed to ionic liquids for using the treatment or prevention of fungal infections.

Dependent claims

A method of treating a fungal infection in a subject in need thereof, the method comprising:

administering to the subject a composition comprising at least one ionic liquid comprising a quaternary ammonium cation and an undecanoic acid anion, wherein the quaternary ammonium cation comprises choline or any one of C1 to C7;
and wherein the fungal infection is infectious keratitis and/or endophthalmitis.

Dependencies are inferred from the claim text.

A61K 31/14
Amines: quaternary ammonium compounds, e.g. edrophonium, choline
A61K 9/0048
Galenical forms characterised by the site of application: eye, e.g. artificial tears
A61K 31/155
Amines: amidines , e.g. guanidine , isourea , isothiourea
A61K 31/165
Amides, e.g. hydroxamic acids: having aromatic rings, e.g. colchicine, atenolol, progabide

From the US filing history. Foreign family members aren’t listed.

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