Pharmaceutical compositions for use in the therapy of blepharitis
AssigneeNovaliq GmbH
InventorsBernhard Günther, Frank Löscher, Sonja Krösser
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Abstract
The present invention provides a pharmaceutical composition comprising 1-perfluorohexyl-octane (F6H8) for use in the therapy, treatment, prevention or amelioration of anterior or posterior blepharitis, preferably posterior blepharitis or symptoms associated therewith. Furthermore, the present invention provides a pharmaceutical kit for the therapy of anterior or posterior blepharitis or symptoms associated therewith.
Claims12
A method of treating anterior blepharitis, in a patient in need thereof, comprising administering to the patient a pharmaceutical composition consisting of 1-perfluorohexyl-octane (F6H8), and wherein the patient is characterized as having
- (i) a Tear Film Break-Up Time (TFBUT) of up to 10 s,
- (ii) an Ocular Surface Disease Index in the range of from 16 to 55,
- (iii) a Schirmer I Test value of at least 2 mm recorded within 5 min, and
- (iv) an added peripheral corneal and conjunctival Oxford staining grade of up to 10.
Dependencies are inferred from the claim text.