Systems and methods for therapeutic nasal neuromodulation

A method for treating a condition within a nasal cavity of a patient, the method comprising:

• advancing a device comprising a shaft comprising a multi-segment end effector to a location within the nasal cavity of the patient, the multi-segment end effector comprising a first retractable and expandable segment comprising micro-electrode array arranged about a plurality of struts to conform to and accommodate an anatomical structure within the nasal cavity when the first segment is in the expanded state, the plurality of struts comprising:
• a first set of support elements comprising a first pair of loop-shaped struts having a bilateral geometry when the first segment is in the expanded state, wherein a first one of the first pair of loop-shaped struts extends in a first direction perpendicular to a longitudinal axis along which a distal most portion of the shaft lies and is positioned within a first side of a first half of the first segment and a second one of the first pair of loop-shaped struts extends in a second direction perpendicular to the longitudinal axis and is positioned within a second side of the first half of the first segment such that the first pair of looped-shaped struts cooperatively form an inwardly extending concave shape relative to the longitudinal axis,
• a second set of support elements comprising a second pair of loop-shaped struts having a bilateral geometry when the first segment is in the expanded state, wherein a first one of the second pair of loop-shaped struts extends in a third direction perpendicular to the longitudinal axis and is positioned within a first side of a second half of the first segment and a second one of the second pair of loop-shaped struts extends in a fourth direction perpendicular to the longitudinal axis and is positioned within a second side of the second half of the first segment such that the second pair of looped-shaped struts cooperatively form an inwardly extending concave shape relative to the longitudinal axis,
• wherein each of the first and second pairs of loop-shaped struts comprises one or more electrodes of the micro-electrode array;
• deploying the first segment at the location to an expanded state such that at least the first pair and the second pair of loop-shaped of struts contact multiple locations along multiple portions of the anatomical structure;
• and
• delivering energy, via one or more electrodes of the micro-electrode array, at a level sufficient to create multiple micro-lesions in tissue of the anatomical structure that interrupt neural signals to mucus producing and/or mucosal engorgement elements.