Systems and methods for production of Xenon-133

A method for producing Xenon-133 comprising:

• collecting an off gas from a Molybdenum-99 production process in a storage tank, the off gas including Xenon-133 and Krypton-85;
• directing the off gas through a cooled charcoal column assembly such that Xenon-133 is selectively adsorbed onto the charcoal column assembly relative to Krypton-85;
• heating the charcoal column assembly to a sufficient temperature to desorb the Xenon-133 from the charcoal column assembly;
• flowing a carrier gas through the heated charcoal column assembly such that the Xenon-133 is desorbed from the charcoal column assembly;
• and
• directing the carrier gas and the desorbed Xenon-133 through a cooled coil assembly such that the Xenon-133 condenses within the coil assembly.