Anti-human MUC1 antibody Fab fragment
AssigneeAstellas Pharma Inc.
InventorsAkifumi Morinaka, Hiroki Shirai, Kazunori Hirayama, Naomi Hosogai, Hitoshi Doihara
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AssigneeAstellas Pharma Inc.
InventorsAkifumi Morinaka, Hiroki Shirai, Kazunori Hirayama, Naomi Hosogai, Hitoshi Doihara
Estimating the term…
The problem to be solved is to provide an anti-human MUC1 antibody Fab fragment that is expected to be useful in the diagnosis and/or treatment of a cancer, particularly, the diagnosis and/or treatment of breast cancer or bladder cancer, and a diagnosis approach and/or a treatment approach using a conjugate comprising the Fab fragment. The solution is an anti-human MUC1 antibody Fab fragment comprising a heavy chain fragment comprising a heavy chain variable region consisting of the amino acid sequence represented by SEQ ID NO: 8 or 10, and a light chain comprising a light chain variable region consisting of the amino acid sequence represented by SEQ ID NO: 12, and a conjugate comprising the Fab fragment.
A conjugate, comprising one or more labeling moieties and an anti-human MUC1 antibody fab fragment, wherein said anti-human MUC1 antibody Fab fragment is selected from the group consisting of the following (a) and (b):
Dependencies are inferred from the claim text.