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US 11,674,126 B2Granted
Biotechnological production of cannabinoids
AssigneeTechnische Universitaet Dortmund
InventorsOliver Kayser, Felix-Oliver Stehle
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Abstract
A method for the recombinant production of cannabigerolic acid in a host organism may use a modified prenyltransferase. A modified prenyltransferase, a nucleic acid molecule that codes for the modified prenyltransferase, and a recombinant organism that includes the modified prenyltransferase and/or the nucleic acid are also disclosed here.
Claims12
A method for recombinant production of cannabigerolic acid in a host organism, the method comprising:
- introducing into the host organism a nucleic acid molecule which comprises a first heterologous nucleotide sequence which encodes a modified prenyltransferase;
- wherein the first heterologous nucleotide sequence has a nucleotide sequence as specified in SEQ ID NO:
- 15, SEQ ID NO:
- 16, SEQ ID NO:
- 18, or SEQ ID NO:
- 3;
- culturing the host organism under conditions to express the nucleotide sequence for encoding the modified prenyltransferase;
- and
- culturing the host organism under conditions to produce cannabigerolic acid.
6 more elements
Dependencies are inferred from the claim text.