Anti-biotin antibody and application thereof

An anti-biotin antibody, wherein the antibody includes complementary determinant regions (CDR) of a heavy chain and a light chain, the heavy chain of the antibody includes three complementary determinant regions including CDR-H1, CDR-H2, and CDR-H3, and the light chain of the antibody includes other three complementary determinant regions including CDR-L1, CDR-L2 and CDR-L3, the CDR-H1, the CDR-H2, the CDR-H3, the CDR-L1, the CDR-L2 and the CDR-L3 of the antibody comprising the following polypeptide sequences:

• (1) the CDR-H1 comprising at least 6 amino acid sequences of SEQ ID NO:
• 1, the sequence being SSYWIC;
• (2) the CDR-H2 comprising at least 18 amino acid sequences of SEQ ID NO:
• 2, the sequence being CIDAGSSGSTYYARWVNG;
• (3) the CDR-H3 comprising at least 14 amino acid sequences of SEQ ID NO:
• 3, the sequence being EGDWGAPIYYGVDL;
• (4) the CDR-L1 comprising at least 13 amino acid sequences of SEQ ID NO:
• 4, the sequence being QSSQSVYNNNQLS;
• (5) the CDR-L2 comprising at least 7 amino acid sequences of SEQ ID NO:
• 5, the sequence being YASTLAS;
• (6) the CDR-L3 comprising at least 12 amino acid sequences of SEQ ID NO:
• 6, the sequence being LGGYYDYADTSA,
• wherein, the anti-biotin antibody specifically binds to non-free biotin.