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US 11,672,853 B2Granted
Methods and compositions for immunization against virus
AssigneeAcademia Sinica
InventorsChi-Huey Wong, Che Ma, Cheng-Chi Wang, Juine-Ruey Chen
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AssigneeAcademia Sinica
InventorsChi-Huey Wong, Che Ma, Cheng-Chi Wang, Juine-Ruey Chen
Estimating the term…
Immunogenic compositions comprising partially glycosylated viral glycoproteins for use as vaccines against viruses are provided. Vaccines formulated using mono-, di-, or tri-glycosylated viral surface glycoproteins and polypeptides provide potent and broad protection against viruses, even across strains. Pharmaceutical compositions comprising monoglycosylated hemagglutinin polypeptides and vaccines generated therefrom and methods of their use for prophylaxis or treatment of viral infections are disclosed. Methods and compositions are disclosed for influenza virus HA, NA and M2, RSV proteins F, G and SH, Dengue virus glycoproteins M or E, hepatitis C virus glycoprotein E1 or E2 and HIV glycoproteins gp120 and gp41.
An immunogenic composition for raising an immune response to a pathogen of viral, bacterial, fungal or other origin, the composition comprising:
A vaccine comprising:
Dependencies are inferred from the claim text.