Bacteriophage compositions comprising respiratory antibacterial phages and methods of use thereof

A pharmaceutical composition comprising a bacteriophage mixture comprising nucleic acids having nucleotide sequences SEQ ID NO:1, SEQ ID NO:3, and SEQ ID NO:5.

A pharmaceutical composition comprising at least three bacteriophages, wherein all of the bacteriophages in the composition are obtained from culturing a plurality of cultures of Pseudomonas aeruginosa infected with a bacteriophage and isolating from each of the plurality of cultures the bacteriophage therein to include in the pharmaceutical composition,

• wherein the plurality of cultures consist of three to eight cultures, and
• wherein the plurality of cultures comprises a first culture of P. aeruginosa infected with a first bacteriophage with a nucleic acid having the nucleotide sequence which has at least 97% sequence identity to SEQ ID NO:1, a second culture of P. aeruginosa infected with a second bacteriophage with a nucleic acid having the nucleotide sequence which has at least 97% sequence identity to SEQ ID NO:3, and a third culture of P. aeruginosa infected with a third bacteriophage with a nucleic acid having the nucleotide sequence which has at least 97% sequence identity to SEQ ID NO:5.