Skin contact adhesive and methods for its preparation and use
AssigneeDow Silicones Corporation
InventorsBizhong Zhu, Martin Grasmann, Vinita Pandit, David Pierre, Bertrand Louis Julien Lenoble
Life of this patent
Estimating the term…
Abstract
A crosslinkable composition is useful for preparing a skin contact adhesive or a coating on a substrate. The crosslinkable composition includes (A) a polyurethane-polyorganosiloxane copolymer and (B) a curing catalyst. The skin contact adhesive prepared by crosslinking the crosslinkable composition is useful in applications such as adhesives for medical tapes, adhesives for wound dressings, adhesives for prosthetics, ostomy appliance adhesives, adhesives for medical monitoring appliances, adhesives for scar therapy treatments, adhesives for cosmetic patches, and transdermal drug delivery systems.
Claims19
A skin contact adhesive composition comprising:
- (A) a polyurethane-polyorganosiloxane copolymer of formula
- where each RU is independently a monovalent unsaturated hydrocarbon group;
- each RD is independently a divalent hydrocarbon group or a divalent halogenated hydrocarbon group;
- each RM is independently a monovalent hydrocarbon group or a monovalent halogenated hydrocarbon group;
- each subscript b is independently 0 or 1;
- each subscript a is independently 0 to 100,000;
- and subscript n is 1 to 10,000;
- (B) a curing catalyst,
- optionally (C) a crosslinker, and one or both of (D) and (E), where
- (D) is an active ingredient, and
- (E) is an excipient.
A method comprising:
- 1) Mixing ingredients comprising
- (A) a polyurethane-polyorganosiloxane copolymer of formula
- where each RU is independently a monovalent unsaturated hydrocarbon group;
- each RD is independently a divalent hydrocarbon group or a divalent halogenated hydrocarbon group;
- each RM is independently a monovalent hydrocarbon group or a monovalent halogenated hydrocarbon group;
- each subscript b is independently 0 or 1;
- each subscript a is independently 0 to 100,000;
- and subscript n is 1 to 10,000,
- (B) a curing catalyst,
- optionally (C) a crosslinker, and one or both of (D) and (E), where
- (D) is an active ingredient, and
- (E) is an excipient;
- thereby preparing a skin contact adhesive composition.
A coating composition comprising:
- (a) a crosslinkable composition comprising
- (A) a polyurethane-polyorganosiloxane copolymer of formula
- where each RU is independently a monovalent unsaturated hydrocarbon group;
- each RD is independently a divalent hydrocarbon group or a divalent halogenated hydrocarbon group;
- each RM is independently a monovalent hydrocarbon group or a monovalent halogenated hydrocarbon group;
- each subscript b is independently 0 or 1;
- each subscript a is independently 0 to 100,000;
- and subscript n is 1 to 10,000,
- (B) a curing catalyst, and
- optionally (C) a crosslinker, and
- (b) a coating additive.
Dependencies are inferred from the claim text.