Continuous method for producing Grignard adducts and a device for carrying out same
AssigneeFraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
InventorsGabriele Menges-Flanagan, Christian Hofmann
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Abstract
The invention relates to a continuous method for the production of Grignard adducts, in which the magnesium chips are activated mechanically in situ. Furthermore, the invention relates to a device for implementation of the method according to the invention.
Claims20
A continuous method for producing a Grignard adduct, wherein said continuous method is conducted in only one reactor, wherein a flow consisting of an alkyl- or aryl halide and a water-free solvent and a further flow consisting of magnesium chips are fed to the reactor such that the magnesium chips drop downwards and form a packed bed in which the chips abut each other, wherein the magnesium chips are fed such that a molar excess of the magnesium chips is present in the reactor relative to the alkyl-or aryl halide, the average dwell time of reagents in the reactor is 1.0 to 20.0 minutes, and the magnesium chips are activated mechanically in the reactor, without utilizing an agitator, but by friction of the magnesium chips against each other triggered by vibrations such that a passivation layer or passivation layers located on a surface of the magnesium chips is/are removed, said vibrations further causing compaction of the activated magnesium chips, and wherein a degree of conversion of the alkyl- or aryl halide to a Grignard adduct at an output of the reactor is at least 90%, wherein the continuous method does not utilize ultrasound to activate the magnesium chips.
A continuous method for producing a Grignard adduct, wherein said continuous method is conducted in only one reactor, wherein the reactor is temperature- controlled at a temperature of 10° C. to 60° C., wherein a flow consisting of an alkyl- or aryl halide and a water-free solvent and a further flow consisting of magnesium chips are fed to the reactor such that the magnesium chips drop downwards and abut each other to form a packed bed, wherein the magnesium chips are fed such that a molar excess of the magnesium chips is present in the reactor relative to the alkyl- or aryl halide, the average dwell time of reagents in the reactor is 1.0 to 20.0 minutes, and the magnesium chips are activated mechanically in the reactor, without utilizing an agitator, by friction of the magnesium chips against each other triggered by vibrations which create a wobbling motion of the magnesium chips such that a passivation layer or passivation layers located on a surface of the magnesium chips is/are removed and further cause a compaction of the activated magnesium chips, and wherein a degree of conversion of the alkyl- or aryl halide to a Grignard adduct at an output of the reactor is at least 90%, wherein the continuous method does not utilize ultrasound to activate the magnesium chips.
Dependencies are inferred from the claim text.