System and method to control nucleation of bubbles
AssigneeOakwood Healthcare, Inc.
InventorJames Richard Spears
Life of this patent
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Abstract
Generation of bubbles is disclosed to occur within a flow of an aqueous fluid. The bubbles may be formed within a tube of a selected diameter and the bubbles are controlled to exit the tube at a selected diameter. Generally, bubbles are formed to include a diameter of less than 1 millimeter, including less than about 20 microns.
Claims20
A system to generate bubbles of a selected size, comprising:
- a container having a volume configured to hold a fluid at a selected pressure;
- a tube having an inner surface and an outer surface and extending from a proximal portion at the container, wherein the tube includes (i) a selected internal diameter defined by the inner surface and (ii) extends to a terminal end at a distal end;
- and
- a selected nucleation site formed within the tube from between the terminal end at the distal end and the proximal portion, wherein the selected nucleation site is configured to generate a bubble filled with a gas when the fluid passes the selected nucleation site;
- wherein the generated bubbles are operable to be delivered to a host fluid;
- wherein the selected nucleation site extends along the inner surface of the tube at an opened access portion of the tube to allow access to the inner surface of the tube that extends from the terminal end to the proximal portion, wherein the opened access is formed by an angled wall of the tube that extends at an acute angle from near the terminal end to the proximal portion;
- wherein the opened access portion includes a portion of the tube near the selected nucleation site that is removed to form the angled wall and form the open access;
- wherein the open access allows access to at least a portion of the internal surface to an ion beam;
- wherein the selected nucleation site includes an ion beam formed pit or crevice in the internal surface or an ion beam deposited material on the internal surface.
A method of generating bubbles with a tube, comprising:
- providing a tube having an internal surface with defects having a dimension not greater than about 1 micron;
- forming an augmented portion in a nucleation region of the tube, wherein the nucleation region includes interacting with the internal surface with an ion beam or depositing material on the internal surface with the ion beam;
- flowing a fluid passed the nucleation region to cause bubbles to nucleate in the augmented portion;
- and
- shearing the bubbles after nucleation with the flowing fluid;
- wherein the augmented portion extends along the internal surface of the tube, wherein an opened access portion of the tube extends from a distal terminal end of the tube to a point proximal the distal terminal end formed by an angled wall of the tube formed by a removed portion of the tube;
- wherein the opened access portion is near the augmented portion and includes a portion of the tube that is removed to form the angled wall and form the opened access;
- wherein the opened access allows access to at least a portion of the internal surface to an ion beam.
A method of generating bubbles with a tube, comprising:
- providing a tube having an internal surface with defects having a dimension not greater than about 1 micron;
- forming an augmented portion in a nucleation region of the tube;
- flowing a fluid passed the nucleation region to cause bubbles to nucleate in the augmented portion;
- shearing the bubbles after nucleation with the flowing fluid;
- wherein forming the augmented portion includes forming a depression within an internal wall of the tube having a dimension about 0.05 microns to about 5 microns;
- wherein forming the depression includes sputtering material with an ion beam through an opened access portion of the tube from the internal surface of the tube on the internal wall to remove material from the internal surface;
- wherein the opened access portion is near the augmented portion and includes a portion of the tube that is removed to form the angled wall and form the opened access;
- and
- wherein the augmented portion extends along the opened access portion of the tube from the terminal end of the tube to a point proximal the terminal end that is formed by an angled wall of the tube.
A method of generating bubbles with a tube, comprising:
- providing a tube having an internal surface with defects having a dimension not greater than about 1 micron;
- forming an augmented portion in a nucleation region of the tube;
- flowing a fluid passed the nucleation region to cause bubbles to nucleate in the augmented portion;
- and
- shearing the bubbles after nucleation with the flowing fluid;
- wherein forming the augmented portion includes forming a mound on an internal wall of the tube;
- wherein forming the mound on the internal wall includes depositing material on an internal surface of the internal wall through an opened access portion of the tube with focused ion beam deposition;
- wherein the augmented portion extends along the opened access portion of the tube from the terminal end of the tube to a point proximal the terminal end that is formed by an angled wall of the tube;
- wherein the opened access portion is near the augmented portion and includes a portion of the tube that is removed to form the angled wall and form the opened access.
A system to generate bubbles of a selected size, comprising:
- a container having a volume configured to hold a fluid at a selected pressure;
- a tube extending from the container, wherein the tube includes (i) a selected internal diameter defined by an internal surface, (ii) a terminal end, and (iii) an angled wall extending from the terminal end to a point proximal the terminal end to form an opened access portion to allow open access to a nucleation region within the tube along the angled wall;
- a trigger connected to a valve, wherein actuation of the trigger opens the valve to allow release of the fluid from the container through the tube;
- and
- a selected nucleation site formed through the opened access portion within the tube in the nucleation region configured to generate a bubble filled with a gas when the fluid passes the selected nucleation site when released from the container;
- wherein the generated bubbles are sheared at the selected nucleation site to achieve a selected size and are operable to be delivered to a host fluid;
- wherein the opened access portion includes a portion of the tube near the selected nucleation site that is removed to form the angled wall of the tube and form the opened access;
- wherein the opened access allows access to at least a portion of the internal surface to an ion beam;
- wherein the selected nucleation site includes an ion beam formed pit or crevice in the internal surface or an ion beam deposited material on the internal surface.
Dependencies are inferred from the claim text.