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US 11,654,012 B2Granted
Connective tissue to bone interface scaffolds
AssigneeSparta Biopharma Inc.
InventorsDushyanth R. Surakanti, Adam B. Yanke, Adam W. Martinez, Kurt W. S. Klitzke, Travis E. Entrop, Dimitrios J. Angelis, Eric A. Nauman, Darryl A. Dickerson
Life of this patent
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Abstract
Connective tissue-to-bone interface scaffolds (e.g., ligament-to-bone interface scaffolds, tendon-to-bone interface scaffolds, etc.). These scaffolds may be a single integrated implant or may be a modular (e.g., two-part) implant system.
Claims22
A method of repairing an enthesis, the method comprising:
- removing a region of a cortical layer of a bone to expose a marrow material in an attachment region;
- anchoring one or more suture to the bone;
- securing a graft that is flexible, compressible and compliant to the attachment region, the graft having a length, a width and a thickness, wherein the thickness is less than half the length and half the width, the graft further comprising:
- a first layer of demineralized bone and a second layer of mineralized bone that is continuously adjacent to the first layer, wherein the second layer has a thickness that is less than 1.5 mm, further wherein securing the graft to the attachment region comprises securing the second layer of the graft in contact with the marrow material, wherein the second layer compliantly conforms to the attachment region;
- and
- suturing a tendon against the first layer using the one or more sutures.
3 more elements
A method of repairing an enthesis, the method comprising:
- removing a region of a cortical layer of a bone to expose a marrow material to form an attachment region, wherein the attachment region has a length of between 10 and 50 mm, a width of between 6 and 25 mm;
- anchoring one or more suture to the bone;
- placing a graft that is flexible, compressible and compliant against the attachment region, the graft having a length, a width and a thickness, wherein the thickness is less than half the length and half the width, the graft further comprising:
- a first layer of demineralized bone and a second layer of mineralized bone that is continuously adjacent to the first layer of demineralized bone, wherein the second layer of mineralized bone has a thickness that is less than 1.5 mm;
- securing the graft to the bone so that the second layer of mineralized bone is in contact with the marrow material and so that the graft compliantly conforms to the attachment region, so marrow material infiltrates into the second layer of mineralized bone;
- and
- suturing a tendon against the first layer of demineralized bone using the one or more suture.
4 more elements
Dependencies are inferred from the claim text.