Chiral stationary phase
AssigneeNankai University
InventorsYao Chen, Zhenjie Zhang, Sainan Zhang
Life of this patent
Estimating the term…
Abstract
A chiral stationary phase comprises a porous framework material and biomolecules. The porous framework material includes one of the metal-organic framework (MOF) material, the covalent organic framework (COF) material and the hydrogen-bonded organic framework (HOF) material. The biomolecules are biological chiral resolving agents. A pore size of the porous framework material is 0.2-15 nm. The porous framework material serves as a solid carrier. The biomolecules are loaded into the porous framework material. The porous framework material is modified with one or more of carboxyl, hydroxyl, amino, aldehyde, double bonds and mercapto groups.
Claims11
A chiral stationary phase, comprising porous framework materials and biomolecules, wherein:
- the porous framework materials include at least one of metal-organic framework materials (MOFs), covalent organic framework materials (COFs) and hydrogen-bonded organic framework materials (HOFs);
- the biomolecules are biological chiral resolving agents;
- a pore size of the porous framework materials is 0.2-15 nm;
- the porous framework materials serve as solid carrier;
- the biomolecules are loaded into the porous framework materials;
- and
- the porous framework materials are modified with one or more of carboxyl, hydroxyl, amino, aldehyde, double bonds and mercapto groups.
Dependencies are inferred from the claim text.