US 11,648,216 B2Granted

Fluorophenyl beta-hydroxyethylamines and their use in the treatment of hyperglycaemia

AssigneeAtrogi AB

InventorsBenjamin Pelcman, Tore Bengtsson

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There is herein provided a compound of formula (I).

Dependent claims

A pharmaceutical composition comprising (R)-2-(tert-Butylamino)-1-(3-fluorophenyl)ethan-1-ol, having the structure:

or a pharmaceutically acceptable salt thereof, and optionally one or more pharmaceutically acceptable adjuvant, diluent and/or carrier;
wherein the (R)-2-(tert-Butylamino)-1-(3-fluorophenyl)ethan-1-ol is present in an enanteromeric excess of at least 90%.

Dependencies are inferred from the claim text.

A61K 31/137
Having aromatic rings , e.g. ketamine, nortriptyline: arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
C07C 215/30
And containing six-membered aromatic rings: containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon…
A61K 31/167
Having aromatic rings, e.g. colchicine, atenolol, progabide: having the nitrogen of a carboxamide group directly attached to the aromatic ring,…
A61P 3/10
For glucose homeostasis: for hyperglycaemia, e.g. antidiabetics

From the US filing history. Foreign family members aren’t listed.

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