Extract, consumable product and method for enriching bioactive metabolite in an extract
AssigneeBrightseed, Inc.
InventorsLee Heil Chae, James Flatt, Alexandra Marcela Herrmann, Gabriel Navarro, Jessica Leigh Ochoa
Life of this patent
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Abstract
This disclosure relates to methods and compositions with enhanced levels of one or more tyramine containing hydroxycinnamic acid amides. Also disclosed herein are methods for producing a consumable product with enhanced levels of a tyramine containing hydroxycinnamic acid amide. Some embodiments relate to a composition enriched with a tyramine containing hydroxycinnamic acid.
Claims20
A method for producing a consumable product with enhanced levels of a tyramine containing hydroxycinnamic acid amide, comprising:
- (a) subjecting a plant for producing a compound of Formula I
- wherein
- R1, R2, R3, R4, R5, R6, R7, R8, and R9 are each independently selected from hydrogen, deuterium, hydroxyl, halogen, cyano, nitro, optionally substituted amino, optionally substituted C-amido, optionally substituted N-amido, optionally substituted ester, optionally substituted —(O)C1-6alkyl, optionally substituted —(O)C1-6alkenyl, optionally substituted —(O)C1-6alkynl, optionally substituted, —(O)C4-12cycloalkyl, optionally substituted —(O)C1-6alkylC4-12cycloalkyl, optionally substituted —(O)C4-12 heterocyclyl, optionally substituted —(O)C1-6alkylC4-12 heterocyclyl, optionally substituted —(O)C4-12 aryl, optionally substituted —(O)C1-6alkylC5-12 aryl, optionally substituted —(O)C1-12 heteroaryl, and optionally substituted —(O)C1-6alkylC1-12heteroaryl;
- the dashed bond is present or absent;
- X is CH2 or O;
- Z is CHRa, NRa, or O;
- and
- Ra is selected from hydrogen, deuterium, hydroxyl, halogen, cyano, nitro, optionally substituted amino, optionally substituted C-amido, optionally substituted N-amido, optionally substituted ester, optionally substituted —(O)C1-6alkyl, optionally substituted —(O)C1-6alkenyl, optionally substituted —(O)C1-6alkynl, optionally substituted, —(O)C4-12cycloalkyl, optionally substituted —(O)C1-6alkylC4-12cycloalkyl, optionally substituted —(O)C4-12heterocyclyl, optionally substituted —(O)C1-6alkylC4-12heterocyclyl, optionally substituted —(O)C4-12aryl, optionally substituted —(O)C1-6alkylC5-12aryl, optionally substituted —(O)C1-12heteroaryl, and optionally substituted —(O)C1-6alkylC1-12heteroaryl,
- the dashed bond is present or absent,
- to at least one biotic or abiotic stress;
- further subjecting the plant to air flow;
- and
- wherein, the subjecting is in combination with at least one enzyme, a glucan, citric acid, a fungal isolate, a tyramine solution, or a combination thereof,
- (b) incorporating the plant or extract thereof into a consumable product.
A method for producing a consumable product with enhanced levels of a tyramine containing hydroxycinnamic acid amide, comprising:
- (a) subjecting a plant for producing a compound of Formula II
- wherein
- R1, R2, and R3 are each independently present or absent, and when present is a substituent on one or more ring atoms (e.g., position 2, 3, and/or 4) and is for each ring atom independently a hydroxy group, halo group, substituted or unsubstituted lower alkyl group, or substituted or unsubstituted lower alkoxy group,
- the dashed bond is present or absent,
- to at least one biotic or abiotic stress;
- further subjecting the plant to air flow;
- and
- wherein, the subjecting is in combination with at least one enzyme, a glucan, citric acid, a fungal isolate, a tyramine solution, or a combination thereof,
- (b) incorporating the plant or extract thereof into a consumable product.
Dependencies are inferred from the claim text.