Compositions and methods for the treatment of xerostomia
AssigneeCellix Bio Private Limited
InventorMahesh Kandula
Life of this patent
Estimating the term…
Abstract
The invention relates to the compounds or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, formula II, formula III, formula IV and formula V and the methods for the treatment of xerostomia may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, lozenge, spray, intravenous, oral solution, buccal mucosal layer tablet, parenteral administration, syrup, or injection. Such compositions may be used to treatment of oral mucosal inflammatory, dry mouth or oral dry mouth mediated infectious diseases.
Claims4
A compound of Formula I:
- or pharmaceutically acceptable hydrates, solvates, prodrugs, enantiomers, or stereoisomers thereof, wherein RH independently represents 2,2-dichloroacetic acid, 2-oxoglutaric acid, 4-aminosalicylic acid, adipic acid, camphoric acid, cinnamic acid, dodecylsulfuric acid, formic acid, galactaric acid, gentisic acid, glucuronic acid, glutaric acid, glycerophosphoric acid, glycolic acid, hippuric acid, isobutyric acid, malonic acid, naphthalene-1,5-disulfonic acid, naphthalene-2-sulfonic acid, nicotinic acid, pyroglutamic acid, sebacic acid, thiocyanic acid, omega 3 fatty acids, omega 6 fatty acids, n-acetyl cysteine (nac), furoate, methyl furoate, ethyl furoate, aminocaproic acid, alpha lipoic acid, R-lipoic acid, or linolelaidic acid.
Dependencies are inferred from the claim text.