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US 11,634,726 B2Granted
Cas9 nucleic acid molecules and their use
AssigneeEmory University
InventorsChristopher B. Doering, H. Trent Spencer, Harrison C. Brown
Life of this patent
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Abstract
Described are recombinant nucleic acid molecules for increased expression of Cas9 in human liver. In some embodiments, the recombinant nucleic acid molecules are provided in compositions and methods for gene editing, specifically using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR).
Claims14
A recombinant nucleic acid molecule comprising a nucleotide sequence encoding Cas9, wherein the sequence is at least 95% identical to SEQ ID NO:
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Dependencies are inferred from the claim text.