Composition and methods for producing tobacco plants and products having reduced tobacco-specific nitrosamines (TSNAs)
AssigneeAltria Client Services LLC
InventorsChengalrayan Kudithipudi, Dongmei Xu, James Strickland
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Abstract
The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
Claims21
Cured leaf of a modified tobacco plant, wherein said cured leaf comprises a reduced level of one or more tobacco-specific nitrosamines (TSNAs), an increased amount of protein activity in a protein comprising a sequence having at least 90% identity to SEQ ID NO:
- 13, and further comprises an increased level of one or more antioxidants, wherein said reduced and increased levels are compared to a control cured leaf of an unmodified tobacco plant of the same variety when grown and cured under comparable conditions;
- and wherein said increased amount of protein activity is a result of the modification in said modified tobacco plant.
Cured leaf of a modified tobacco plant, wherein said cured leaf comprises a reduced level of nitrite, an increased amount of protein activity in a protein comprising a sequence having at least 90% identity to SEQ ID NO:
- 13, comprises an increased level of one or more antioxidants, wherein said reduced and increased levels are compared to a control cured leaf of an unmodified tobacco plant of the same variety when grown and cured under comparable conditions;
- and wherein said increased amount of protein activity is a result of the modification in said modified tobacco plant.
Dependencies are inferred from the claim text.