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AssigneeCodexis, Inc.
InventorsJovana Nazor, Robert Osborne, Jack Liang, Jonathan Vroom, Xiyun Zhang, David Entwistle, Rama Voladri, Ravi David Garcia, Jeffrey C. Moore, Shane Grosser, Birgit Kosjek, Matthew Truppo
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The present invention provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proline hydroxylases, and methods of using the engineered proline hydroxylases to prepare compounds useful in the production of active pharmaceutical agents.
An expression vector comprising a polynucleotide comprising SEQ ID NO:1007, 1008, or 1009 with up to 20 nucleotide substitutions, insertions, or deletions in the polynucleotide sequence of SEQ ID NO:
Dependencies are inferred from the claim text.