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US 11,634,483 B2Granted
Nucleic acids encoding anti-VEGF-A antibodies and uses thereof
AssigneeMedImmune, LLC
InventorsChing Ching Leow, Nazzareno Dimasi, Karen Coffman, Ping Tsui, Changshou Gao, Mario A. Cepeda, Adrian Schwartz Mittelman
Life of this patent
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Abstract
The present invention relates to antibodies having activity against a vascular endothelial growth factor (VEGF), and methods of making and using such antibodies.
Claims4
An isolated nucleic acid molecule comprising polynucleotides encoding an antibody comprising heavy chain complementarity determining regions 1-3 (HCDR1, HCDR2, and HCDR3) and light chain complementarity determining regions 1-3 (LCDR1, LCDR2, and LCDR3), wherein HCDR1, HCDR2, and HCDR3 and LCDR1, LCDR2, and LCDR3 comprise SEQ ID NOs:
- 79-84, respectively.
Dependencies are inferred from the claim text.