Musclin peptides and methods of use thereof
AssigneeUniversity of Iowa Research Foundation
InventorsLeonid Zingman, Denice Hodgson-Zingman
Life of this patent
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Abstract
In certain embodiments, the present invention provides a musclin peptide and methods of increasing muscle growth, performance, resistance to injury and/or preventing or reducing muscle atrophy and improving overall skeletal muscle, metabolic and cardiac health in an animal in need thereof by administering a musclin peptide.
Claims18
A method of increasing muscle growth, performance, resistance to injury and/or preventing or reducing muscle atrophy in an animal in need thereof, comprising administering a musclin peptide consisting of 33 amino acids and consisting of at least 80% identity to SEQ ID NO:2 to the animal.
A method of promoting overall exercise tolerance, physical performance and/or cardiovascular function and/or fitness in an animal in need thereof, comprising administering a musclin peptide consisting of 33 amino acids and consisting of at least 80% identity to SEQ ID NO:2 to the animal.
A method of increasing biogenesis of mitochondria and adaptation of muscle in an animal in need thereof, comprising administering a musclin peptide consisting of 33 amino acids and consisting of at least 80% identity to SEQ ID NO:2 to the animal.
Dependencies are inferred from the claim text.