Method for the purification of collagen

A process for the extraction of collagen from collagen-containing matter derived from jellyfish, comprising the steps of:

• (a) incubating the collagen-containing matter in an acidic solution for at least 1 h at a temperature in the range of about 0° C. to about 37° C. to form an incubant;
• (b) diafiltrating the incubant from step (a) to substantially purify solubilised collagen within the incubant, thereby forming a retentate;
• and
• (c) separating the soluble and insoluble matter of the retentate obtained from step (b) to remove the remaining insoluble matter, wherein the separation is performed by filtration;
• and wherein the process further comprises passing the substantially pure collagen solution obtained from step (c) through a 0.4 m filter to obtain a first filtrate, and then passing that first filtrate through a 0.2 m filter to obtain a second filtrate, wherein the second filtrate is a substantially pure monomeric collagen solution.