Two-dimensional stimuli-responsive covalent organic frameworks with high intrinsic conductivity
AssigneeTrustees of Dartmouth College
InventorsKatherine A. Mirica, Zheng Meng, Robert M. Stolz
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Abstract
In an embodiment, the present disclosure pertains to a method of sensing an analyte in a sample by: (1) exposing the sample to an electrode that includes a covalent-organic framework with a plurality of metal-coordinated aromatic units that are linked to one another by aromatic linkers; (2) detecting a change in a property of the electrode; and (3) correlating the change in the property to the presence or absence of the analyte. In an additional embodiment, the present disclosure pertains to said covalent-organic frameworks. Additional embodiments of the present disclosure pertain to methods of making the covalent-organic frameworks.
Claims29
A method of sensing an analyte in a sample, said method comprising:
- exposing the sample to an electrode comprising a covalent-organic framework, wherein the covalent-organic framework comprises a plurality of metal-coordinated aromatic units, wherein the metal-coordinated aromatic units are linked to one another by aromatic linkers, wherein the metal-coordinated aromatic units comprise metallophthalocyanine units, and wherein the metallophthalocyanine units comprise octatosylaminophthalocyanine;
- detecting a change in a property of the electrode;
- and
- correlating the change in the property to the presence or absence of the analyte.
A covalent-organic framework comprising:
- a plurality of metal-coordinated aromatic units,
- wherein the metal-coordinated aromatic units are linked to one another by aromatic linkers,
- wherein the metal-coordinated aromatic units comprise metallophthalocyanine units,
- wherein the metallophthalocyanine units comprise octaamino-nickelphtalocyanine, and
- wherein the covalent-organic framework is in the form of a fully aromatic and conjugated structure.
A method of sensing an analyte in a sample, said method comprising:
- exposing the sample to an electrode comprising a covalent-organic framework, wherein the covalent-organic framework comprises a plurality of metal-coordinated aromatic units, wherein the metal-coordinated aromatic units are linked to one another by aromatic linkers, wherein the aromatic linkers comprise pyrenes, and wherein the pyrenes comprise pyrenetetraone;
- detecting a change in a property of the electrode;
- and
- correlating the change in the property to the presence or absence of the analyte.
A method of sensing an analyte in a sample, said method comprising:
- exposing the sample to an electrode comprising a covalent-organic framework, wherein the covalent-organic framework comprises a plurality of metal-coordinated aromatic units, wherein the metal-coordinated aromatic units are linked to one another by aromatic linkers, wherein the aromatic linkers and the metal-coordinated aromatic frameworks are linked through pyrazine rings, and wherein the pyrazine rings comprise phenazine;
- detecting a change in a property of the electrode;
- and
- correlating the change in the property to the presence or absence of the analyte.
A method of sensing an analyte in a sample, said method comprising:
- exposing the sample to an electrode comprising a covalent-organic framework, wherein the covalent-organic framework comprises a plurality of metal-coordinated aromatic units, wherein the metal-coordinated aromatic units are linked to one another by aromatic linkers;
- detecting a change in a property of the electrode, wherein the detected change in the property of the electrode is a change in normalized conductance, and wherein the change in normalized conductance is characterized by the following formula:
- −ΔG/G0=−(I0−I)/I0×100%, where −ΔG/G0 represents normalized conductance, Io represents initial current, and I represents current at various points during measurement;
- and
- correlating the change in the property to the presence or absence of the analyte.
A covalent-organic framework comprising:
- a plurality of metal-coordinated aromatic units, wherein the metal-coordinated aromatic units are linked to one another by aromatic linkers, wherein the aromatic linkers comprise pyrenes, and wherein the pyrenes comprise pyrenetetraone, and
- wherein the covalent-organic framework is in the form of a fully aromatic and conjugated structure.
A covalent-organic framework comprising:
- a plurality of metal-coordinated aromatic units,
- wherein the metal-coordinated aromatic units are linked to one another by aromatic linkers, wherein the aromatic linkers and the metal-coordinated aromatic frameworks are linked through pyrazine rings, and wherein the pyrazine rings comprise phenazine, and
- wherein the covalent-organic framework is in the form of a fully aromatic and conjugated structure.
Dependencies are inferred from the claim text.