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US 11,634,434 B2Granted
Bifunctional alpha-synuclein binding agents and uses thereof
AssigneeUniversity of Saskatchewan
InventorsJoseph Kakish, Edward Krol, Jeremy Lee, Kevin Allen
Life of this patent
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Abstract
Bifunctional molecules having first and second alpha-synuclein binding agents coupled by a linker are disclosed. The bifunctional molecules have potential utility in the diagnosis, treatment and/or prophylaxis of disorders in which alpha-synuclein is implicated, including Parkinson's disease. Methods of making and using the bifunctional molecules are disclosed.
Claims9
A bifunctional molecule comprising a first alpha-synuclein binding agent covalently linked to a second alpha-synuclein binding agent by a linker, comprising one of the following structures (II) or (III):
- wherein n is an integer between 1 and 10 carbon atoms that defines a linker, wherein the linker is a saturated or unsaturated alkyl linker.
Dependencies are inferred from the claim text.