Disposable device for filtering a large medium volume
AssigneeSartorius Stedim Biotech GmbH
InventorsJohannes Wortmeyer, Maik Sommer, Thomas Friese, Thomas Loewe
Life of this patent
Estimating the term…
Abstract
A single-use device for filtration of a large volume of medium including a plurality of single-use filter units, at least some of which, preferably all of which, are connected to each other by rigid pipes. The filter units include at least one prefilter and at least one main filter for virus filtration which is configured as a hollow fiber capsule.
Claims24
A single-use filtration device for filtering a large volume of medium, comprising:
- a plurality of single-use filter units, at least some of which are connected to each other by rigid pipes, the filter units including a plurality of prefilters and a plurality of main filters for virus filtration which are configured as hollow fiber capsules;
- a common outlet pipe for the plurality of prefilters;
- at least one shut-off valve between the prefilters and the main filters in the common outlet pipe allowing a grouping of all of the plurality of main filters separate from the prefilters,
- the plurality of main filters having vent connections on their upper front sides opening into a common vent pipe which leads to an unfiltrate-side sterile air filter, configured so that test gas can be supplied via the sterile air filter through the common vent pipe to all of the plurality of main filters to jointly test integrity of the plurality of main filters.
A method of performing an integrity test in a single-use filtration device for filtering a large volume of medium, the single-use filtration device comprising a plurality of prefilters, a plurality of main filters for virus filtration which are configured as hollow fiber capsules, and a common outlet pipe for the plurality of prefilters, a shut-off valve being provided between the prefilters and the main filters in the common outlet pipe, the plurality of main filters having vent connections on their upper front sides opening into a common vent pipe which leads to an unfiltrate-side sterile air filter, the method comprising steps of:
- grouping all of the plurality of main filters independently of the plurality of prefilters by closing the shut-off valve to shut off the plurality of main filters from the plurality of prefilters, and
- supplying a test gas via the sterile air filter through the common vent pipe to all of the plurality of main filters.
Dependencies are inferred from the claim text.