Graft scaffold for cartilage repair and process for making same
AssigneeETH Zurich
InventorsMatti Kesti, Marcy Zenobi-Wong, Michael Muller
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Abstract
The present invention relates to a method of providing a graft scaffold for cartilage repair, particularly in a human patient. The method of the invention comprising the steps of providing particles and/or fibres; providing an aqueous solution of a gelling polysaccharide; providing mammalian cells; mixing said particles and/or fibres, said aqueous solution of a gelling polysaccharide and said mammalian cells to obtain a printing mix; and depositing said printing mix in a three-dimensional form. The invention further relates to graft scaffolds and grafts obtained by the method of the invention.
Claims18
A graft scaffold comprising:
- 3% to 3.5% (w/v) of a gelling polysaccharide selected from the group consisting of gellan gum, acylated and sulfated gellan gum;
- mammalian cells;
- and
- alginate,
- wherein the graft scaffold is obtainable by a method comprising:
- providing an aqueous solution of the gelling polysaccharide and alginate;
- providing mammalian cells;
- mixing said aqueous solution of a gelling polysaccharide and alginate, and said mammalian cells to obtain a printing mix;
- and
- depositing said printing mix in a three-dimensional form, thereby obtaining the graft scaffold.
Dependencies are inferred from the claim text.