Human anti-VEGFR-2/KDR antibodies

A nucleic acid encoding an antibody or antigen binding fragment thereof that binds to human VEGFR2, the antibody or antigen binding fragment thereof comprising a heavy chain variable domain, which comprises a CDR1H, a CDR2H, and a CDR3H sequence, and a light chain variable domain, which comprises a CDR1L, a CDR2L, and a CDR3L sequence wherein:

• (i) the CDR1H sequence is GFTFSWYVMG (SEQ ID NO:
• 237);
• (ii) the CDR2H sequence is SIYPQGGATSYADSVKG (SEQ ID NO:
• 238);
• (iii) the CDR3H sequence is GNYFDY (SEQ ID NO:
• 241);
• (iv) the CDR1L sequence is RASQSVSSNYFG (SEQ ID NO:
• 245);
• (v) the CDR2L sequence is GASSRAT (SEQ ID NO:
• 246);
• and
• (vi) the CDR3L sequence is QQFDSLPLT (SEQ ID NO:
• 247).