Silk-based product formulations and methods of use

A silk-based product (SBP) for ocular lubrication comprising processed silk fibroin, and optionally at least one ocular therapeutic agent,

• wherein the processed silk fibroin has been degummed, dissolved in 5-13 M lithium bromide, and stressed by heating the silk fibroin to 60° C. or autoclaving the silk fibroin,
• wherein a 0.05 to 5% w/v solution of the processed silk fibroin has a surface tension of between about 30 mN/m and 60 mN/n, and
• wherein a 0.05 to 5% w/v solution of the processed silk fibroin has a viscosity of between 30-400 cP.