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US 11,633,441 B2Granted
Immuno-modulated replication-efficient vaccinia virus strain
AssigneesSutter Gerd, Rojas Exposito Juan José
InventorsGerd Sutter, Juan José Rojas Exposito
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Abstract
The invention refers to new immuno-modulated replication-efficient Vaccinia virus strain (IOVA) and its derivatives for the use in medicine.
Claims14
A genetically modified, immuno-modulating Vaccinia virus, wherein the virus is identified by the presence of SEQ ID No.:
- 1, has a functional active K1L, is replication competent in mammalian cells, and induces calreticulin transiocation to the membrane of an infected HeLa cell.
Dependencies are inferred from the claim text.